I played for a few days using 352. It's good defensively because LM / RM goes down in line with the three CB (that means you need LM / RM with good defensive qualities because if you use LB / RB in those positions, CHEM decreases badly ) but the middle does not exist. The transition is too fast between the lines and you don't have time to intercept the opposing players. The two CDM settings may need to be changed. Anyway, congratulations on as many such ****yzes as possible!
I have Handerson 94 with Anchor in a 442 sistem (i play with a midfilder with more defensive duties). Its a god idea to change Handerson 94 with Sissoko 94?
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